Tg(Cspg4-EGFP*)HDbe
Transgene Detail
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Symbol: |
Tg(Cspg4-EGFP*)HDbe |
Name: |
transgene insertion H, Dwight E Bergles |
MGI ID: |
MGI:5568765 |
Synonyms: |
NG2-mEGFP, NG2-mEGFP-H |
Transgene: |
Tg(Cspg4-EGFP*)HDbe Location: unknown
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Alliance: |
Tg(Cspg4-EGFP*)HDbe page
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Transgene Type: |
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Transgenic (Reporter) |
Mutation: |
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Insertion
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Mutation details: Bacterial artificial chromosome (BAC) library (CHORI) was used to obtain a BAC (#RP23-309G21) containing the entire mouse Cspg4 (chondroitin sulfate proteoglycan 4) gene. The BAC was modified to create a membrane anchored form of EGFP (enhanced green fluorescent protein) under the control of the Cspg4 promoter followed by a polyadenylation sequence. EGFP is targeted to the plasma membrane by fusing the first 26 amino acids (containing two palmitoylation domains and a myristoylation domain) of Lck (lymphocyte-specific protein tyrosine kinase) to the EGFP N terminal.
(J:209866)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Original: |
J:209866 Hughes EG, et al., Oligodendrocyte progenitors balance growth with self-repulsion to achieve homeostasis in the adult brain. Nat Neurosci. 2013 Jun;16(6):668-76 |
All: |
4 reference(s) |
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