Khdrbs2^tm1.1Schei
Targeted Allele Detail

Summary

• Symbol: Khdrbs2^tm1.1Schei
• Name: KH domain containing, RNA binding, signal transduction associated 2; targeted mutation 1.1, Peter Scheiffele
• MGI ID: MGI:5568964
• Synonyms: Slm1^KO
• Gene: Khdrbs2 Location: Chr1:32211795-32697649 bp, + strand Genetic Position: Chr1, 11.86 cM, cytoband B
• Alliance: Khdrbs2^tm1.1Schei page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:208331
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exon2 and an FRT-flanked neo cassette flanked by two loxP sites were removed following cre-mediated recombination. Western blot analysis showed an absent of protein expression. (J:208331)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Khdrbs2 Mutation: 25 strains or lines available

References

• Original: J:208331 Iijima T, et al., Neuronal cell type-specific alternative splicing is regulated by the KH domain protein SLM1. J Cell Biol. 2014 Feb 3;204(3):331-42
• All: 3 reference(s)