About   Help   FAQ
Gpsm3tm1.1(KOMP)Wtsi
Targeted Allele Detail
Summary
Symbol: Gpsm3tm1.1(KOMP)Wtsi
Name: G-protein signalling modulator 3 (AGS3-like, C. elegans); targeted mutation 1.1, Wellcome Trust Sanger Institute
MGI ID: MGI:5569069
Gene: Gpsm3  Location: Chr17:34808780-34810728 bp, + strand  Genetic Position: Chr17, 18.17 cM
Alliance: Gpsm3tm1.1(KOMP)Wtsi page
IMPC: Gpsm3 gene page
Mutation
origin
Mutant Cell Line:  EPD0384_5_C01
Germline Transmission:  Earliest citation of germline transmission: J:204739
Parent Cell Line:  JM8A1.N3 (ES Cell)
Strain of Origin:  C57BL/6N-Atm1Brd
Project Collection: KOMP-CSD
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion     Vector: L1L2_Bact_P
 
Mutation detailsCre-mediated excision of the parental Gpsm3tm1(KOMP)Wtsi allele resulted in the removal of the neomycin selection cassette and critical exon(s) leaving behind the inserted lacZ reporter sequence. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml. (J:204739)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 8 assay results
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gpsm3 Mutation:  9 strains or lines available
References
Original:  J:204739 International Knockout Mouse Consortium, MGI download of modified allele data from IKMC and creation of new knockout alleles. Database Download. 2014-2023;
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/12/2024
MGI 6.24
The Jackson Laboratory