Tas1r1^tm2(cre)Uboe
Targeted Allele Detail

Summary

• Symbol: Tas1r1^tm2(cre)Uboe
• Name: taste receptor, type 1, member 1; targeted mutation 2, Ulrich Boehm
• MGI ID: MGI:5569262
• Synonyms: Tas1r1^BLiC
• Gene: Tas1r1 Location: Chr4:152112371-152122947 bp, - strand Genetic Position: Chr4, 82.83 cM
• Alliance: Tas1r1^tm2(cre)Uboe page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:200616
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutations: Insertion, Intragenic deletion
• Tas1r1^tm2(cre)Uboe expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Tas1r1 (MGI:1927505)

• Mutation details: The Tas1r1 conding region was replaced with an expression cassette encoding the barley lectin sequence linked through an internal ribosome entry cassette to the cre recombinase sequence. This allele produces a bicistronic transcript from the Tas1r1 promoter. (J:200616)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Tas1r1 (mouse) Summary of all recombinase alleles driven by Tas1r1. Alliance mouse Tas1r1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tas1r1 Mutation: 27 strains or lines available

References

• Original: J:200616 Foster SR, et al., Expression, regulation and putative nutrient-sensing function of taste GPCRs in the heart. PLoS One. 2013;8(5):e64579
• All: 2 reference(s)