Atg14^tm1Aki
Targeted Allele Detail

Summary

• Symbol: Atg14^tm1Aki
• Name: autophagy related 14; targeted mutation 1, Shizuo Akira
• MGI ID: MGI:5569340
• Synonyms: Atg14^f, Atg14^flox, mAtg14L^Neor+flox
• Gene: Atg14 Location: Chr14:47778350-47805891 bp, - strand Genetic Position: Chr14, 24.6 cM
• Alliance: Atg14^tm1Aki page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:206181
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A floxed allele was inserted upstream of exon 4. An additional loxP site was inserted downstream of exon 4. (J:158180)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atg14 Mutation: 41 strains or lines available

References

• Original: J:206181 Patel KK, et al., Autophagy proteins control goblet cell function by potentiating reactive oxygen species production. EMBO J. 2013 Dec 11;32(24):3130-44
• All: 19 reference(s)