Sry^em1Takas
Endonuclease-mediated Allele Detail

Summary

• Symbol: Sry^em1Takas
• Name: sex determining region of Chr Y; endonuclease-mediated mutation 1, Shuji Takada
• MGI ID: MGI:5569481
• Gene: Sry Location: ChrY:2662471-2663658 bp, - strand Genetic Position: ChrY, cytoband p
• Alliance: Sry^em1Takas page

Mutation origin

• Strain of Origin: (C57BL/6 x DBA/2)F1

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Insertion
• Mutation details: TALEN targeting produced a two nucleotide (TT) insertion that results in a frameshift mutation in founder ID3. (J:207780)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sry Mutation: 54 strains or lines available

References

• Original: J:207780 Kato T, et al., Production of Sry knockout mouse using TALEN via oocyte injection. Sci Rep. 2013;3:3136
• All: 1 reference(s)