Mirc31^tm1.1Sjm
Targeted Allele Detail

Summary

• Symbol: Mirc31^tm1.1Sjm
• Name: microRNA cluster 31, including Mirlet7c-2 through Mirlet7b; targeted mutation 1.1, Sean J Morrison
• MGI ID: MGI:5569518
• Synonyms: let-7b/c2^flox
• Gene: Mirc31 Location: Chr15:85590804-85591604 bp Genetic Position: Chr15, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:207231
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Mirlet7c-2 through Mirlet7b was floxed. Flp-mediated recombination removed the FRT flanked neomycin resistance cassette inserted downstream of Mirlet7b. (J:207231)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mirc31 Mutation: 2 strains or lines available

References

• Original: J:207231 Nishino J, et al., A network of heterochronic genes including Imp1 regulates temporal changes in stem cell properties. Elife. 2013;2:e00924
• All: 2 reference(s)