Tg(AGER)#Eca
Transgene Detail

Summary

• Symbol: Tg(AGER)#Eca
• Name: transgene insertion, Eleonora Cavarra
• MGI ID: MGI:5569820
• Synonyms: RAGE, Tg(hRAGE)
• Transgene: Tg(AGER)#Eca Location: unknown
• Alliance: Tg(AGER)#Eca page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(AGER)#Eca expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  AGER (177)

  Ager	(MGI:893592)

• Mutation details: This transgene consists of a 8.1-kb human bacterial artificial chromosome (BAC) clone, BACRP11-346J19, containing the entire genomic sequence of human AGER, including the endogenous promoter. Western blot and immunohistochemistry confirmed expression in the lung. The pound symbol (#) is used when line is not specified and/or lines are pooled. (J:205092)

Disease models

Expression

In Structures Affected by this Mutation:

9 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:205092 Fineschi S, et al., Receptor for advanced glycation end products contributes to postnatal pulmonary development and adult lung maintenance program in mice. Am J Respir Cell Mol Biol. 2013 Feb;48(2):164-71
• All: 1 reference(s)