Tg(Myh6-Mylk3)3Hkas
Transgene Detail

Summary

• Symbol: Tg(Myh6-Mylk3)3Hkas
• Name: transgene insertion 3, Hideko Kasahara
• MGI ID: MGI:5569925
• Synonyms: TG3
• Transgene: Tg(Myh6-Mylk3)3Hkas Location: unknown
• Alliance: Tg(Myh6-Mylk3)3Hkas page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Myh6-Mylk3)3Hkas expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Mylk3 (MGI:2443063)

• Mutation details: The promoter drives cardiac-specific expression of an HA-tagged cDNA. Three lines were generated (TG1 6.5-fold increase in expression, TG2 21-fold and TG3 21-fold). (J:210147)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:210147 Warren SA, et al., Myosin light chain phosphorylation is critical for adaptation to cardiac stress. Circulation. 2012 Nov 27;126(22):2575-88
• All: 1 reference(s)