Ckap5^tm1.1Eba
Targeted Allele Detail

Summary

• Symbol: Ckap5^tm1.1Eba
• Name: cytoskeleton associated protein 5; targeted mutation 1.1, Elisa Barbarese
• MGI ID: MGI:5570192
• Synonyms: TOG^floxed
• Gene: Ckap5 Location: Chr2:91357107-91451009 bp, + strand Genetic Position: Chr2, 50.63 cM, cytoband E1
• Alliance: Ckap5^tm1.1Eba page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:205779
• Parent Cell Line: D1 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6J)F1

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The targeting construct consists of a loxP sequence inserted into intron 3 and a frt-PGKNeo-frt-loxP cassette inserted in intron 6 of the BAC clone RP23-118G11. The frt flanked Neo was removed via FLP-mediated recombination. (J:205779)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ckap5 Mutation: 95 strains or lines available

References

• Original: J:205779 Barbarese E, et al., Conditional knockout of tumor overexpressed gene in mouse neurons affects RNA granule assembly, granule translation, LTP and short term habituation. PLoS One. 2013;8(8):e69989
• All: 2 reference(s)