Herpud1tm1Kame
Targeted Allele Detail
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Symbol: |
Herpud1tm1Kame |
Name: |
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1; targeted mutation 1, Koichi Kokame |
MGI ID: |
MGI:5571583 |
Gene: |
Herpud1 Location: Chr8:95113066-95122005 bp, + strand Genetic Position: Chr8, 46.46 cM, cytoband C5
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Alliance: |
Herpud1tm1Kame page
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Decreased cerebral infarction size in Herpud1tm1Kame/Herpud1tm1Kame mice following temporary three-vessel occlusion
Show the 1 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:210654
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: An IRES, lacZ and neomycin resistance cassette replaced exons 2 through 8. Western blot analysis confirmed the absence of protein expression in the liver, pancreas and kidney.
(J:210654)
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Generation of the Herpud1tm1Kame allele |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Herpud1 Mutation: |
30 strains or lines available
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Original: |
J:210654 Eura Y, et al., Derlin-1 deficiency is embryonic lethal, Derlin-3 deficiency appears normal, and Herp deficiency is intolerant to glucose load and ischemia in mice. PLoS One. 2012;7(3):e34298 |
All: |
3 reference(s) |
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