Patz1^tm1.2Welm
Targeted Allele Detail

Summary

• Symbol: Patz1^tm1.2Welm
• Name: POZ (BTB) and AT hook containing zinc finger 1; targeted mutation 1.2, Wilfried Ellmeier
• MGI ID: MGI:5572819
• Synonyms: Mazr^F
• Gene: Patz1 Location: Chr11:3239131-3259083 bp, + strand Genetic Position: Chr11, 2.3 cM
• Alliance: Patz1^tm1.2Welm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:209168
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

Allele Type: Targeted (Conditional ready, No functional change) Mutation: Insertion Mutation details: A floxed neomycin resistance cassette was inserted within intron 1 and a single loxP site 5' to exon 1 by homologous recombination. Cre-mediated recombination removed the selection cassette and left exon 1 floxed. (J:158947)

Generation of the Patz1^tm1.2Welm allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Patz1 Mutation: 55 strains or lines available

References

• Original: J:209168 Abramova A, et al., The transcription factor MAZR preferentially acts as a transcriptional repressor in mast cells and plays a minor role in the regulation of effector functions in response to FcepsilonRI stimulation. PLoS One. 2013;8(10):e77677
• All: 5 reference(s)