Kcna10^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Kcna10^tm1Lex
• Name: potassium voltage-gated channel, shaker-related subfamily, member 10; targeted mutation 1, Lexicon Genomics
• MGI ID: MGI:5574085
• Synonyms: Kcna10^TM45
• Gene: Kcna10 Location: Chr3:107090459-107103037 bp, + strand Genetic Position: Chr3, 46.64 cM
• Alliance: Kcna10^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:210785
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEvBrd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• A IRES-beta-geo and puromycin resistance cassette replaced exon 2, the entire coding sequence. (J:210785)

Disease models

Expression

In Mice Carrying this Mutation:	23 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kcna10 Mutation: 26 strains or lines available

References

• Original: J:210785 Lee SI, et al., A null mutation of mouse Kcna10 causes significant vestibular and mild hearing dysfunction. Hear Res. 2013 Jun;300:1-9
• All: 1 reference(s)