Noc3l^tm1Maim
Targeted Allele Detail

Summary

• Symbol: Noc3l^tm1Maim
• Name: NOC3 like DNA replication regulator; targeted mutation 1, Masayoshi Imagawa
• MGI ID: MGI:5574094
• Gene: Noc3l Location: Chr19:38776572-38807681 bp, - strand Genetic Position: Chr19, 33.42 cM
• Alliance: Noc3l^tm1Maim page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:210767
• Parent Cell Line: EGR-G01 (ES Cell)
• Strain of Origin: (129S2/SvPas x C57BL/6NSlc)F1-Tg(CAG-EGFP,Acr-EGFP)2Osb

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A neomycin resistance cassette replaced exons 6 through part of 9. (J:210767)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Noc3l Mutation: 39 strains or lines available

Notes

EGR-G01 cells carry one copy of Tg(CAG-EGFP,Acr-EGFP)2Osb. J:210767 does not specify whether the transgene is present in the line of mice created.

References

• Original: J:210767 Ochiai N, et al., Targeted disruption of fad24, a regulator of adipogenesis, causes pre-implantation embryonic lethality due to the growth defect at the blastocyst stage. Biochem Biophys Res Commun. 2013 Aug 23;438(2):301-5
• All: 1 reference(s)