Zeb2^tm2.1Yhi
Targeted Allele Detail

Summary

• Symbol: Zeb2^tm2.1Yhi
• Name: zinc finger E-box binding homeobox 2; targeted mutation 2.1, Yujiro Higashi
• MGI ID: MGI:5574184
• Synonyms: Sip1^SIP1-EGFP
• Gene: Zeb2 Location: Chr2:44873644-45007407 bp, - strand Genetic Position: Chr2, 27.31 cM, cytoband C1
• Alliance: Zeb2^tm2.1Yhi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:207850
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

Allele Type: Targeted (Reporter) Mutations: Insertion, Intragenic deletion Mutation details: A floxed neomycin resistance cassette was inserted upstream of exon 9. A EGFP reporter was inserted in-frame with the coding sequence in exon 9. Cre-mediated recombination removed the selection cassette. (J:207850)

Generation of Zeb2^tm2.1Yhi allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Zeb2 Mutation: 78 strains or lines available

References

• Original: J:207850 Nishizaki Y, et al., SIP1 expression patterns in brain investigated by generating a SIP1-EGFP reporter knock-in mouse. Genesis. 2014 Jan;52(1):56-67
• All: 9 reference(s)