Galntl5^tm1Nari
Targeted Allele Detail

Summary

• Symbol: Galntl5^tm1Nari
• Name: UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 5; targeted mutation 1, Hisashi Narimatsu
• MGI ID: MGI:5574442
• Gene: Galntl5 Location: Chr5:25386458-25425295 bp, + strand Genetic Position: Chr5, 12.33 cM, cytoband A3
• Alliance: Galntl5^tm1Nari page

Deformed or ventral flexuous sperm in Galntl5^tm1Nari/Galntl5⁺ males

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:206466
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

Allele Type: Targeted (Null/knockout) Mutation: Intragenic deletion The second exon that contains the start codon was replaced with a neo-cassette. (J:206466)

Generation of the Galntl5^tm1Nari allele

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Galntl5 Mutation: 32 strains or lines available

References

• Original: J:206466 Takasaki N, et al., A heterozygous mutation of GALNTL5 affects male infertility with impairment of sperm motility. Proc Natl Acad Sci U S A. 2014 Jan 21;111(3):1120-5
• All: 1 reference(s)