About   Help   FAQ
Adcy3Jll
Chemically induced Allele Detail
Summary
Symbol: Adcy3Jll
Name: adenylate cyclase 3; Jll
MGI ID: MGI:5574448
Synonyms: Adcy3Jll-Gek, Adcy3M279I
Gene: Adcy3  Location: Chr12:4183397-4263525 bp, + strand  Genetic Position: Chr12, 1.99 cM, cytoband A-B
Alliance: Adcy3Jll page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsENU mutagenesis induced a G to A transition that results in the amino acid substitution of methionine-to-isoleucine at position 279 (M279I). (J:223554)
Inheritance:    Dominant
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Adcy3 Mutation:  43 strains or lines available
References
Original:  J:223554 Pitman JL, et al., A gain-of-function mutation in adenylate cyclase 3 protects mice from diet-induced obesity. PLoS One. 2014;9(10):e110226
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/12/2024
MGI 6.24
The Jackson Laboratory