Tg(Tbx4-cre/ERT2)#Kras
Transgene Detail

Summary

• Symbol: Tg(Tbx4-cre/ERT2)#Kras
• Name: transgene insertion, Mark Krasnow
• MGI ID: MGI:5574488
• Synonyms: Tbx4^LME-CreERT2, Tbx4LME^CreERT2
• Transgene: Tg(Tbx4-cre/ERT2)#Kras Location: unknown
• Alliance: Tg(Tbx4-cre/ERT2)#Kras page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Tbx4-cre/ERT2)#Kras expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Tbx4 (MGI:102556)

• Mutation details: The lung mesenchyme specific enhancer from the mouse promoter and a minimal Hsp68 promoter drive expression of an inducible fusion cre recombinase gene (cre/ERT2). The pound symbol is used when no line is specified and/or lines are pooled. (J:217397)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Tbx4 (mouse) Summary of all recombinase alleles driven by Tbx4. Comparative matrix view of recombinase activities Alliance mouse Tbx4 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:189012 Greif DM, et al., Radial construction of an arterial wall. Dev Cell. 2012 Sep 11;23(3):482-93
• All: 6 reference(s)