Tg(Cck-cre,-lacZ)1Mini
Transgene Detail
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Symbol: |
Tg(Cck-cre,-lacZ)1Mini |
Name: |
transgene insertion 1, Liliana Minichiello |
MGI ID: |
MGI:5574585 |
Synonyms: |
BAC-Cck-Cre, Cck-cre |
Transgene: |
Tg(Cck-cre,-lacZ)1Mini Location: unknown
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Alliance: |
Tg(Cck-cre,-lacZ)1Mini page
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Strain of Origin: |
(CBA x C57BL/6)
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Transgene Type: |
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Transgenic (Recombinase, Reporter) |
Mutation: |
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Insertion
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Tg(Cck-cre,-lacZ)1Mini expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Cck (MGI:88297) |
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Mutation details: A BAC (RP23-26B6) containing the Cck gene was modified by ET recombination so that a cassette composed of a hybrid intron, a cre recombinase gene, an internal ribosomal entry site (IRES), a beta-galactosidase gene (lacZ), and a neomycin/kanamycin resistance marker was inserted into the first ATG of the first coding exon (exon 2). The neo/kan marker was removed using flp recombinase. The purified construct was injected into the pronuclei of (CBA x C57BL/6) hybrid oocytes.
(J:210229)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Cck
(mouse)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:210229 Geibel M, et al., Ablation of TrkB signalling in CCK neurons results in hypercortisolism and obesity. Nat Commun. 2014;5:3427 |
All: |
2 reference(s) |
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