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Iah1tm1b(EUCOMM)Hmgu
Targeted Allele Detail
Summary
Symbol: Iah1tm1b(EUCOMM)Hmgu
Name: isoamyl acetate-hydrolyzing esterase 1 homolog; targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
MGI ID: MGI:5574600
Gene: Iah1  Location: Chr12:21366363-21373608 bp, + strand  Genetic Position: Chr12, 8.3 cM
Alliance: Iah1tm1b(EUCOMM)Hmgu page
IMPC: Iah1 gene page
Mutation
origin
Mutant Cell Line:  HEPD0531_2_E06
Germline Transmission:  Earliest citation of germline transmission: J:204739
Parent Cell Line:  JM8.N4 (ES Cell)
Strain of Origin:  C57BL/6N
Project Collection: EUCOMM
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion     Vector: L1L2_Pgk_P
 
Mutation detailsCre-mediated excision of the parental Iah1tm1a(EUCOMM)Hmgu allele resulted in the removal of the promoter-driven neomycin selection cassette and critical exon(s) leaving behind the inserted lacZ reporter sequence. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml. (J:204739)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Iah1 Mutation:  13 strains or lines available
References
Original:  J:204739 International Knockout Mouse Consortium, MGI download of modified allele data from IKMC and creation of new knockout alleles. Database Download. 2014-2023;
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory