Ephb4^tm1.1Jwu
Targeted Allele Detail

Summary

• Symbol: Ephb4^tm1.1Jwu
• Name: Eph receptor B4; targeted mutation 1.1, Jiangping Wu
• MGI ID: MGI:5575404
• Synonyms: Ephb4^fl
• Gene: Ephb4 Location: Chr5:137348371-137372784 bp, + strand Genetic Position: Chr5, 76.38 cM
• Alliance: Ephb4^tm1.1Jwu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:206160
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP-flanked exon 1 was inserted via homologous recombination. Flp-mediated recombination removed the FRT-flanked neomyocin resistance cassette. (J:206160, J:222563)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ephb4 Mutation: 43 strains or lines available

References

• Original: J:206160 Jin W, et al., Effect of reduced EPHB4 expression in thymic epithelial cells on thymocyte development and peripheral T cell function. Mol Immunol. 2014 Mar;58(1):1-9
• All: 5 reference(s)