Dlx1^tm1Rth
Targeted Allele Detail

Summary

• Symbol: Dlx1^tm1Rth
• Name: distal-less homeobox 1; targeted mutation 1, David H Rowitch
• MGI ID: MGI:5575408
• Synonyms: Dlx1/Dlx2^tm1.1Rth
• Gene: Dlx1 Location: Chr2:71358457-71364325 bp, + strand Genetic Position: Chr2, 42.61 cM
• Alliance: Dlx1^tm1Rth page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:212992
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: (C57BL/6 x 129S/SvEv)F1

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• A loxP site was introduced to intron 1. (J:212992)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Dlx1 Mutation: 21 strains or lines available

Notes

This allele was generated in ES cells in conjunction with Dlx2^tm1.1Rth.

References

• Original: J:212992 Silbereis JC, et al., Olig1 function is required to repress dlx1/2 and interneuron production in Mammalian brain. Neuron. 2014 Feb 5;81(3):574-87
• All: 5 reference(s)