Kif18a^tm1Zgwg
Targeted Allele Detail

Summary

• Symbol: Kif18a^tm1Zgwg
• Name: kinesin family member 18A; targeted mutation 1, Zhugang Wang
• MGI ID: MGI:5575486
• Gene: Kif18a Location: Chr2:109111165-109172094 bp, + strand Genetic Position: Chr2, 56.55 cM
• Alliance: Kif18a^tm1Zgwg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:211103
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin resistance cassette replaced part of exon 2. Immunohistochemistry confirmed the absence of protein expression in testes. (J:211103)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kif18a Mutation: 63 strains or lines available

References

• Original: J:211103 Liu XS, et al., Germinal Cell Aplasia in Kif18a Mutant Male Mice Due to Impaired Chromosome Congression and Dysregulated BubR1 and CENP-E. Genes Cancer. 2010 Jan;1(1):26-39
• All: 1 reference(s)