Sod1^m1H
Chemically induced Allele Detail

Summary

• Symbol: Sod1^m1H
• Name: superoxide dismutase 1, soluble; mutation 1, Harwell
• MGI ID: MGI:5575771
• Synonyms: Sod1^D83G
• Gene: Sod1 Location: Chr16:90017650-90023221 bp, + strand Genetic Position: Chr16, 51.56 cM, cytoband B5-C3
• Alliance: Sod1^m1H page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced an A to G transition in exon 3 that results in an aspartic acid to glycine missense mutation (D83G). Dismutase activity of the mutant protein is severely reduced compared to the wild-type protein. (J:169366, J:219360)

Disease models

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Sod1 Mutation: 39 strains or lines available

References

• Original: J:169366 MouseBook^TM, Information obtained from MouseBook^TM, Medical Research Council Mammalian Genetics Unit, Harwell, UK. Unpublished. 2005-2013
• All: 2 reference(s)