Tg(LHX3-cre)#Sjr
Transgene Detail

Summary

• Symbol: Tg(LHX3-cre)#Sjr
• Name: transgene insertion, Simon J Rhodes
• MGI ID: MGI:5576209
• Synonyms: ELHX3^Cre
• Transgene: Tg(LHX3-cre)#Sjr Location: unknown
• Alliance: Tg(LHX3-cre)#Sjr page

Transgene origin

• Strain of Origin: C3HeB/FeJ

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(LHX3-cre)#Sjr expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  human

  LHX3 (8022)

  Lhx3	(MGI:102673)

• Mutation details: The 7.9 kb 3' enhancer fragment of the human LHX3 gene and a 920 bp Hsp68 minimal promoter were cloned into an EGFP-cre expression vector to generate the transgenic construct. The linearized construct was microinjected into E0.5 d C3HeB/FeJ embryos to generate founders. Founder or line numbers are not available. (J:211401)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	LHX3 (human) Summary of all recombinase alleles driven by LHX3. Comparative matrix view of recombinase activities Alliance human LHX3 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:211401 Park S, et al., Cell-specific actions of a human LHX3 gene enhancer during pituitary and spinal cord development. Mol Endocrinol. 2013 Dec;27(12):2013-27
• All: 1 reference(s)