Zfp335^blt
Chemically induced Allele Detail

Summary

• Symbol: Zfp335^blt
• Name: zinc finger protein 335; blood T cells low
• MGI ID: MGI:5576210
• Synonyms: bloto
• Gene: Zfp335 Location: Chr2:164733802-164753677 bp, - strand Genetic Position: Chr2, 85.27 cM
• Alliance: Zfp335^blt page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Chemically induced (ENU) (Hypomorph)
• Mutation: Single point mutation
• Mutation details: An arginine-to-tryptophan (CGG->TGG) change at amino acid 1092 in exon 21 was generated through ENU mutagenesis. This mutation affects one of the C-terminal zinc fingers. The R1092W mutation does not effect protein expression or stability. (J:214793)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Zfp335 Mutation: 67 strains or lines available

References

• Original: J:214793 Han BY, et al., Zinc finger protein Zfp335 is required for the formation of the naive T cell compartment. Elife. 2014;3
• All: 1 reference(s)