Tg(Scgb1a1-Muc5b,-AcGFP)#Evns
Transgene Detail

Summary

• Symbol: Tg(Scgb1a1-Muc5b,-AcGFP)#Evns
• Name: transgene insertion, Christopher M Evans
• MGI ID: MGI:5576314
• Transgene: Tg(Scgb1a1-Muc5b,-AcGFP)#Evns Location: unknown
• Alliance: Tg(Scgb1a1-Muc5b,-AcGFP)#Evns page

Transgene origin

• Strain of Origin: C57BL/6N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Tg(Scgb1a1-Muc5b,-AcGFP)#Evns expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Muc5b (MGI:1921430)

• Mutation details: This transgene consists of the airway specific rat Scgb1a1 promoter, the full-length mouse Muc5b genomic DNA, and an IRES-AcGFP (Aequorea coerulescens green fluorescent protein). Two lines were generated, however the pound symbol (#) is used when line is not specified and/or lines are pooled. Western blot and immunohistochemistry confirmed expression of the transgene in the lungs. (J:207159)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:207159 Roy MG, et al., Muc5b is required for airway defence. Nature. 2014 Jan 16;505(7483):412-6
• All: 2 reference(s)