Ppard^{tm1(PPARD)Bsls}
Targeted Allele Detail

Summary

• Symbol: Ppard^{tm1(PPARD)Bsls}
• Name: peroxisome proliferator activator receptor delta; targeted mutation 1, Bart Staels
• MGI ID: MGI:5576390
• Synonyms: Ppardelta^KI
• Gene: Ppard Location: Chr17:28451715-28520446 bp, + strand Genetic Position: Chr17, 14.64 cM
• Alliance: Ppard^{tm1(PPARD)Bsls} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:211453
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Humanized sequence, Inserted expressed sequence, Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A floxed neomycin resistance cassette and the human cDNA replaced the coding sequence of exons 3 through 8. (J:211453)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ppard Mutation: 68 strains or lines available

References

• Original: J:211453 Gross B, et al., Generation and characterization of a humanized PPARdelta mouse model. Br J Pharmacol. 2011 Sep;164(1):192-208
• All: 1 reference(s)