Timp4^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Timp4^tm1Lex
• Name: tissue inhibitor of metalloproteinase 4; targeted mutation 1, Lexicon Genomics
• MGI ID: MGI:5576463
• Synonyms: LEXKO-1224
• Gene: Timp4 Location: Chr6:115221405-115229166 bp, - strand Genetic Position: Chr6, 53.29 cM
• Alliance: Timp4^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:211441
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S5/SvEvBrd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Not Specified
• No molecular details provided.

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Timp4 Mutation: 14 strains or lines available

References

• Original: J:211441 Basu R, et al., TIMP3 is the primary TIMP to regulate agonist-induced vascular remodelling and hypertension. Cardiovasc Res. 2013 Jun 1;98(3):360-71
• All: 4 reference(s)