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Tg(CAG-Ubqln1)2Hmw
Transgene Detail
Summary
Symbol: Tg(CAG-Ubqln1)2Hmw
Name: transgene insertion 2, Hongmin Wang
MGI ID: MGI:5576803
Transgene: Tg(CAG-Ubqln1)2Hmw  Location: unknown  
Alliance: Tg(CAG-Ubqln1)2Hmw page
Transgene
origin
Strain of Origin:  C57BL/6 x SJL
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(CAG-Ubqln1)2Hmw expresses 1 gene
 
Mutation detailsThe transgene expresses a full-length mouse Ubqln1 cDNA under the control of the CMV enhancer/chicken beta-actin promoter. Immunoblot analysis indicates striking overexpression in the brain, heart, liver and skeletal muscle with lower levels of overexpression seen in other tissues. (J:206930)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:206930 Liu Y, et al., Ubiquilin-1 protects cells from oxidative stress and ischemic stroke caused tissue injury in mice. J Neurosci. 2014 Feb 19;34(8):2813-21
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory