Hprt1tm4(CAG-Tbx18*,-Venus)Akis
Targeted Allele Detail
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Symbol: |
Hprt1tm4(CAG-Tbx18*,-Venus)Akis |
Name: |
hypoxanthine phosphoribosyltransferase 1; targeted mutation 4, Andreas Kispert |
MGI ID: |
MGI:5576943 |
Synonyms: |
HprtTbx18VP16 |
Gene: |
Hprt1 Location: ChrX:52077014-52110536 bp, + strand Genetic Position: ChrX, 29.31 cM, cytoband A6
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Alliance: |
Hprt1tm4(CAG-Tbx18*,-Venus)Akis page
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Germline Transmission: |
Earliest citation of germline transmission:
J:210076
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Conditional ready, Inserted expressed sequence, Reporter) |
Mutation: |
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Insertion
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Hprt1tm4(CAG-Tbx18*,-Venus)Akis expresses
1 gene
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Mutation details: The targeting construct inserted into the locus a CAG promoter, loxP site, neomycin resistance/STOP cassette, loxM site, and in an inverted cassette containing loxP and loxM sites, Tbx18 cDNA with a VP16 activator, IRES, Venus reporter sequence and polyadenylation sequence. Cre-mediated recombination is required to achieve expression of the inverted cassette.
(J:210076)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Hprt1 Mutation: |
1279 strains or lines available
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Original: |
J:210076 Greulich F, et al., Tbx18 function in epicardial development. Cardiovasc Res. 2012 Dec 1;96(3):476-83 |
All: |
2 reference(s) |
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