Oca2^p-5Btlr
Chemically induced Allele Detail

Summary

• Symbol: Oca2^p-5Btlr
• Name: oculocutaneous albinism II; pink-eyed dilution 5 Bruce Beutler
• MGI ID: MGI:5578028
• Synonyms: draco1
• Gene: Oca2 Location: Chr7:55889508-56186266 bp, + strand Genetic Position: Chr7, 33.44 cM
• Alliance: Oca2^p-5Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced A to T transversion at base pair 56423352 (v38) on Chromosome 7 in the GenBank genomic region NC_000073. The mutation corresponds to residue 2424 in the NM_021879 mRNA sequence in exon 22 of 24 total exons. The mutation results in a tyrosine (Y) to phenylalanine (F) substitution at residue 765. (J:212065)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Oca2 Mutation: 70 strains or lines available

References

• Original: J:212065 Purrington T, et al., Mutagenetix entry for draco1. MGI Direct Data Submission. 2014
• All: 1 reference(s)