Fasl^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Fasl^m1Btlr
• Name: Fas ligand; mutation 1, Bruce Beutler
• MGI ID: MGI:5578030
• Synonyms: riogrande
• Gene: Fasl Location: Chr1:161608260-161616064 bp, - strand Genetic Position: Chr1, 69.95 cM
• Alliance: Fasl^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced an A to G transition at base pair 161,788,164 (v38) on chromosome 1, or base pair 5,651 in the GenBank genomic region NC_000067. The mutation corresponds to residue 332 in the mRNA sequence NM_010177 within exon 1 of 4 total exons. The mutation results in an aspartic acid (D) to glycine (G) substitution at position 41 (D41G). (J:212067)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Fasl Mutation: 37 strains or lines available

References

• Original: J:212067 Wang K-W, et al., Mutagenetix entry for riogrande. MGI Direct Data Submission. 2014
• All: 1 reference(s)