C1qtnf3^tm1Yiw
Targeted Allele Detail

Summary

• Symbol: C1qtnf3^tm1Yiw
• Name: C1q and tumor necrosis factor related protein 3; targeted mutation 1, Yoichiro Iwakura
• MGI ID: MGI:5578157
• Gene: C1qtnf3 Location: Chr15:10952418-10980236 bp, + strand Genetic Position: Chr15, 5.38 cM, cytoband A2
• Alliance: C1qtnf3^tm1Yiw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:211893
• Parent Cell Line: EGR-101 (ES Cell)
• Strain of Origin: C57BL/6NSlc

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A floxed neomycin resistance cassette replaced exon 4. RT-PCR confirmed the absence of transcript expression in the kidneys. (J:211893)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any C1qtnf3 Mutation: 30 strains or lines available

References

• Original: J:211893 Murayama MA, et al., CTRP3 plays an important role in the development of collagen-induced arthritis in mice. Biochem Biophys Res Commun. 2014 Jan 3;443(1):42-8
• All: 2 reference(s)