Tmprss2^tm3Sho
Targeted Allele Detail

Summary

• Symbol: Tmprss2^tm3Sho
• Name: transmembrane protease, serine 2; targeted mutation 3, Stuart Orkin
• MGI ID: MGI:5578610
• Synonyms: mTmprss2-L-S-L
• Gene: Tmprss2 Location: Chr16:97365882-97412395 bp, - strand Genetic Position: Chr16, 57.53 cM, cytoband C2
• Alliance: Tmprss2^tm3Sho page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:212219
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Not Applicable)
• Mutations: Insertion, Intragenic deletion
• Exon 2 was replaced with a floxed neomycin resistance cassette, stopper cassette and loxP site. (J:212219)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tmprss2 Mutation: 55 strains or lines available

References

• Original: J:212219 Baena E, et al., ETV1 directs androgen metabolism and confers aggressive prostate cancer in targeted mice and patients. Genes Dev. 2013 Mar 15;27(6):683-98
• All: 1 reference(s)