Fdxr^m1J
Spontaneous Allele Detail

Summary

• Symbol: Fdxr^m1J
• Name: ferredoxin reductase; mutation 1 Jackson
• MGI ID: MGI:5581449
• Synonyms: Fdxr^R389Q, stiff
• Gene: Fdxr Location: Chr11:115158850-115167876 bp, - strand Genetic Position: Chr11, 80.84 cM, cytoband E2
• Alliance: Fdxr^m1J page

Mutation origin

• Strain of Origin: B6;129S-Gt(ROSA)26Sor^{tm38(CAG-GCaMP3)Hze}/J

Mutation description

• Allele Type: Spontaneous (Hypomorph)
• Mutation: Single point mutation
• Mutation details: This spontaneous C-to-T transition at chromosome 11 position 115,269,462 bp (GRCm38) causes a p.R389Q substitution and was identified in the same spontaneous mutant mouse as Otop3^m1J. (J:222308)
• Inheritance: Recessive

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Fdxr Mutation: 22 strains or lines available

References

• Original: J:223793 Dionne LA, et al., Stiffened hindquarters, a new spontaneous mutation. MGI Direct Data Submission. 2015
• All: 6 reference(s)