Slc39a5^tm1.1Gka
Targeted Allele Detail

Summary

• Symbol: Slc39a5^tm1.1Gka
• Name: solute carrier family 39 (metal ion transporter), member 5; targeted mutation 1.1, Glen K Andrews
• MGI ID: MGI:5581453
• Gene: Slc39a5 Location: Chr10:128231800-128237098 bp, - strand Genetic Position: Chr10, 76.55 cM, cytoband D3
• Alliance: Slc39a5^tm1.1Gka page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:209760
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Mutation details: A loxP site was inserted in intron 4 and a second loxP site and neomycin resistance cassette were inserted downstream from exon 12. Cre-mediated recombination removed exons 4 through 12 and the selection cassette. (J:209760)

Generation of the Slc39a5^tm1Gka and Slc39a5^tm1.1Gka alleles

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc39a5 Mutation: 28 strains or lines available

References

• Original: J:209760 Geiser J, et al., The zinc transporter Zip5 (Slc39a5) regulates intestinal zinc excretion and protects the pancreas against zinc toxicity. PLoS One. 2013;8(11):e82149
• All: 1 reference(s)