Sult1a1^tm1Glatt
Targeted Allele Detail

Summary

• Symbol: Sult1a1^tm1Glatt
• Name: sulfotransferase family 1A, phenol-preferring, member 1; targeted mutation 1, Hansruedi Glatt
• MGI ID: MGI:5581616
• Gene: Sult1a1 Location: Chr7:126272037-126275604 bp, - strand Genetic Position: Chr7, 69.25 cM
• Alliance: Sult1a1^tm1Glatt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:208180
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: (C57BL/6 x 129/Sv)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• The targeting vector replaced exons 2 through 4 with a neomycin resistance cassette. (J:208180)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sult1a1 Mutation: 12 strains or lines available

References

• Original: J:208180 Herrmann K, et al., Formation of hepatic DNA adducts by methyleugenol in mouse models: drastic decrease by Sult1a1 knockout and strong increase by transgenic human SULT1A1/2. Carcinogenesis. 2014 Apr;35(4):935-41
• All: 4 reference(s)