Gt(ROSA)26Sor^{tm1(CAG-Mafb,-tdTomato)Good}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(CAG-Mafb,-tdTomato)Good}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Lisa Goodrich
• MGI ID: MGI:5581667
• Synonyms: Gt(ROSA)26Sor^CAG-lsl-Mafb, Mafb^CE
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(CAG-Mafb,-tdTomato)Good} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:207904
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm1(CAG-Mafb,-tdTomato)Good} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  mouse	Mafb (MGI:104555)

• Mutation details: The targeting vector inserted into the locus a CAG promoter, floxed neomycin resistance cassette with three polyadenylation sequences, the Mafb coding sequence, an IRES, tdTomato reporter gene and polyadenylation sequence. (J:207904)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 993 strains or lines available

References

• Original: J:207904 Yu WM, et al., A Gata3-Mafb transcriptional network directs post-synaptic differentiation in synapses specialized for hearing. Elife. 2013;2:e01341
• All: 1 reference(s)