Cycs^tm1Arte
Targeted Allele Detail

Summary

• Symbol: Cycs^tm1Arte
• Name: cytochrome c, somatic; targeted mutation 1, TaconicArtemis
• MGI ID: MGI:5581696
• Synonyms: CYC^G41S
• Gene: Cycs Location: Chr6:50539543-50543518 bp, - strand Genetic Position: Chr6, 24.32 cM
• Alliance: Cycs^tm1Arte page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:210495
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Not Applicable)
• Mutation: Nucleotide substitutions
• Mutation details: Nucleotide substitution(s) in the coding sequence result(s) in the amino acid substitution of serine for glycine at position 41 (G41S). This mutation is predicted to increase peroxidase activity. (J:210495)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cycs Mutation: 9 strains or lines available

References

• Original: J:210495 Josephs TM, et al., Enhancing the peroxidase activity of cytochrome c by mutation of residue 41: implications for the peroxidase mechanism and cytochrome c release. Biochem J. 2014 Mar 1;458(2):259-65
• All: 2 reference(s)