Runx2^tm1Javed
Targeted Allele Detail

Summary

• Symbol: Runx2^tm1Javed
• Name: runt related transcription factor 2; targeted mutation 1, Amjad Javed
• MGI ID: MGI:5582325
• Synonyms: Runx2^F
• Gene: Runx2 Location: Chr17:44806873-45125518 bp, - strand Genetic Position: Chr17, 21.33 cM
• Alliance: Runx2^tm1Javed page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:212896
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 8 was floxed. (J:212896)

Expression

In Mice Carrying this Mutation:	43 assay results
In Structures Affected by this Mutation:	10 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Runx2 Mutation: 44 strains or lines available

References

• Original: J:212896 Chen H, et al., Chondrocyte-specific regulatory activity of Runx2 is essential for survival and skeletal development. Cells Tissues Organs. 2011;194(2-4):161-5
• All: 6 reference(s)