Map3k8^m2Btlr
Chemically induced Allele Detail

Summary

• Symbol: Map3k8^m2Btlr
• Name: mitogen-activated protein kinase kinase kinase 8; mutation 2, Bruce Beutler
• MGI ID: MGI:5582496
• Synonyms: juicy
• Gene: Map3k8 Location: Chr18:4331325-4352978 bp, - strand Genetic Position: Chr18, 2.73 cM
• Alliance: Map3k8^m2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU induced a T to G transversion at base pair 4,339,552 (v38) on chromosome 18, or base pair 13,930 in the GenBank genomic region NC_000084. The mutation corresponds to residue 942 in the NM_007746 mRNA sequence in exon 5 of 8 total exons. The mutation results in a leucine (L) to arginine (R) substitution at amino acid residue 273. (J:212899)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Map3k8 Mutation: 41 strains or lines available

References

• Original: J:212899 Wang Y, et al., Mutagenetix entry for juicy. MGI Direct Data Submission. 2014
• All: 1 reference(s)