Cd4^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Cd4^m1Btlr
• Name: CD4 antigen; mutation 1, Bruce Beutler
• MGI ID: MGI:5582497
• Synonyms: craw
• Gene: Cd4 Location: Chr6:124841655-124865184 bp, - strand Genetic Position: Chr6, 59.17 cM
• Alliance: Cd4^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced an C to T transition at base pair 124867746 (v38) on chromosome 6, or base pair 20,465 in the GenBank genomic region NC_000072. The mutation corresponds to residue 1,245 in the NM_013488 mRNA sequence in exon 7 of 10 total exons. The mutation results in substitution of a premature stop codon (*) for glutamine (Q) at amino acid 359. (J:212900)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cd4 Mutation: 85 strains or lines available

References

• Original: J:212900 Wang KW, et al., Mutagenetix entry for craw. MGI Direct Data Submission. 2014
• All: 1 reference(s)