Cnbd2^tm1Dwac
Targeted Allele Detail

Summary

• Symbol: Cnbd2^tm1Dwac
• Name: cyclic nucleotide binding domain containing 2; targeted mutation 1, Dagmar Wachten
• MGI ID: MGI:5582743
• Gene: Cnbd2 Location: Chr2:156154219-156217558 bp, + strand Genetic Position: Chr2, 77.39 cM, cytoband H2
• Alliance: Cnbd2^tm1Dwac page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:207897
• Parent Cell Line: v6.5 (ES Cell)
• Strain of Origin: (C57BL/6 x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A floxed neomycin resistance cassette replaced exons 5 through 7. Western blot analysis confirmed the absence of protein expression in germ cells. (J:207897)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cnbd2 Mutation: 34 strains or lines available

References

• Original: J:207897 Krahling AM, et al., CRIS-a novel cAMP-binding protein controlling spermiogenesis and the development of flagellar bending. PLoS Genet. 2013 Dec;9(12):e1003960
• All: 1 reference(s)