Myo7a^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Myo7a^m1Btlr
• Name: myosin VIIA; mutation 1, Bruce Beutler
• MGI ID: MGI:5582747
• Synonyms: coward
• Gene: Myo7a Location: Chr7:97700267-97768731 bp, - strand Genetic Position: Chr7, 53.57 cM
• Alliance: Myo7a^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a T to G transversion at base pair 98,085,466 (v38) on chromosome 7, or base pair 34,057 in the GenBank genomic region NC_000073. The mutation corresponds to residue 2,113 in the mRNA sequence NM_001256081 within exon 4 of 6 total exons. The mutation results in a leucine (L) to arginine (R) substitution at position 618 (L618R). (J:213050)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Myo7a Mutation: 118 strains or lines available

References

• Original: J:213050 SoRelle J, et al., Mutagenetix entry for coward. MGI Direct Data Submission. 2014
• All: 1 reference(s)