Anpep^tm1Afk
Targeted Allele Detail

Summary

• Symbol: Anpep^tm1Afk
• Name: alanyl aminopeptidase, membrane; targeted mutation 1, Andreas Kolb
• MGI ID: MGI:5582781
• Gene: Anpep Location: Chr7:79471551-79497958 bp, - strand Genetic Position: Chr7, 45.19 cM
• Alliance: Anpep^tm1Afk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:212511
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin resistance cassette replaced exons 2 through 9. Western blot analysis confirmed the absence of protein expression in the liver, kidney and small intestine. (J:212511)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Anpep Mutation: 84 strains or lines available

References

• Original: J:212511 Kolb AF, et al., Mammary gland development is delayed in mice deficient for aminopeptidase N. Transgenic Res. 2013 Apr;22(2):425-34
• All: 2 reference(s)