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Anpeptm1Afk
Targeted Allele Detail
Summary
Symbol: Anpeptm1Afk
Name: alanyl aminopeptidase, membrane; targeted mutation 1, Andreas Kolb
MGI ID: MGI:5582781
Gene: Anpep  Location: Chr7:79471551-79497958 bp, - strand  Genetic Position: Chr7, 45.19 cM
Alliance: Anpeptm1Afk page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:212511
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance cassette replaced exons 2 through 9. Western blot analysis confirmed the absence of protein expression in the liver, kidney and small intestine. (J:212511)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Anpep Mutation:  84 strains or lines available
References
Original:  J:212511 Kolb AF, et al., Mammary gland development is delayed in mice deficient for aminopeptidase N. Transgenic Res. 2013 Apr;22(2):425-34
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory