Tg(HCRT-tTA)G5Ahky
Transgene Detail
|
|
| Symbol: |
Tg(HCRT-tTA)G5Ahky |
| Name: |
transgene insertion G5, Akihiro Yamanaka |
| MGI ID: |
MGI:5582928 |
| Synonyms: |
Orexin-tTA |
| Transgene: |
Tg(HCRT-tTA)G5Ahky Location: unknown
|
| Alliance: |
Tg(HCRT-tTA)G5Ahky page
|
|
|
|
| Transgene Type: |
|
Transgenic (Transactivator) |
| Mutation: |
|
Insertion
|
| |
|
Mutation details: The human prepro-orexin (HCRT) promoter drives the expression of 0.7 kb of the mammalianized tetracycline-controlled transcriptional activator (tTA). In situ hybridization on brain slices confirmed expression in orexin neurons. Lines 29, C5, and G5 show the highest tTA mRNA expression.
(J:212974)
|
|
|
View phenotypes and curated references for all genotypes (concatenated display).
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
|
| Original: |
J:212974 Tabuchi S, et al., Influence of inhibitory serotonergic inputs to orexin/hypocretin neurons on the diurnal rhythm of sleep and wakefulness. Sleep. 2013 Sep;36(9):1391-404 |
| All: |
3 reference(s) |
|
Analysis Tools
