P4htm^tm1Jomy
Targeted Allele Detail

Summary

• Symbol: P4htm^tm1Jomy
• Name: prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum); targeted mutation 1, Johanna Myllyharju
• MGI ID: MGI:5583029
• Synonyms: P4h-tm^-
• Gene: P4htm Location: Chr9:108456061-108474866 bp, - strand Genetic Position: Chr9, 59.52 cM
• Alliance: P4htm^tm1Jomy page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:213191
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: Mutant mice were generated by targeting a LacZNeo cassette into exon 3, leading to a truncated transcript of exons 1-2 and a split exon 3 fused to LacZNeo. (J:213191)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any P4htm Mutation: 71 strains or lines available

References

• Original: J:213191 Laitala A, et al., Transmembrane prolyl 4-hydroxylase is a fourth prolyl 4-hydroxylase regulating EPO production and erythropoiesis. Blood. 2012 Oct 18;120(16):3336-44
• All: 2 reference(s)