Etn3^tm2.1Jwi
Targeted Allele Detail

Summary

• Symbol: Etn3^tm2.1Jwi
• Name: early transposon element insertion site 3; targeted mutation 2.1, Jeffrey W Innis
• MGI ID: MGI:5584134
• Synonyms: Neo^-/eETn⁺
• Gene: Etn3 Location: unknown Genetic Position: ChrX, Syntenic
• Alliance: Etn3^tm2.1Jwi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:207896
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

Allele Type: Targeted (Not Applicable) Mutation: Transposon insertion Mutation details: Using an engineered BAC from Etn3^Ppd mice, the targeting construct replaced exons 2 through 4 of Dusp9 and inserted a neomycin resistance cassette and the 5.5 kb spanning the early transposon element (engineered Etn; eEtn). Flp-mediated recombination removed the selection cassette. (J:207896)

Generation of the Etn3^tm1Jwi, Etn3^tm1.1Jwi, Etn3^tm2Jwi, and Etn3^tm2.1Jwi alleles

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Etn3 Mutation: 1 strain or line available

Notes

ES cell line = UMB6J-D7 (C57BL/6J)

References

• Original: J:207896 Lehoczky JA, et al., A novel intergenic ETnII-beta insertion mutation causes multiple malformations in polypodia mice. PLoS Genet. 2013 Dec;9(12):e1003967
• All: 1 reference(s)