Cntnap4^tm1Pele
Targeted Allele Detail

Summary

• Symbol: Cntnap4^tm1Pele
• Name: contactin associated protein-like 4; targeted mutation 1, Elior Peles
• MGI ID: MGI:5585148
• Synonyms: Cntnap4^tm1Fsh
• Gene: Cntnap4 Location: Chr8:113296675-113609349 bp, + strand Genetic Position: Chr8, 58.7 cM
• Alliance: Cntnap4^tm1Pele page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:211338
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A genomic fragment of 585 bp containing the first exon of the gene, encoding the ATG and the signal sequence, was replaced with an in-frame enhanced green fluorescence protein (EGFP), followed by an oppositely directed neo gene. This allele refers to line no. 149. (J:211338)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cntnap4 Mutation: 70 strains or lines available

References

• Original: J:211338 Karayannis T, et al., Cntnap4 differentially contributes to GABAergic and dopaminergic synaptic transmission. Nature. 2014 Jul 10;511(7508):236-40
• All: 3 reference(s)